551+ Vacation Rentals Near Mayo Clinic Florida |
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Floridarentalvacations - Vacation Rentals in Mayo Clinic Florida

Property Image From $250
         

10.0 (121 Reviews)
House
Perfect Jax beach home min to ocean & restaurants!
  • Air Conditioner
  • Parking
  • Pet Friendly

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Property Image From $387
         

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New
House
Jacksonville Home, Near Beach and Mayo Clinic!
  • Parking
  • Pet Friendly
  • Pool

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Property Image From $134
         

10.0 (54 Reviews)
Apartment
51 m² Apartment ∙ 1 bedroom ∙ 3 guests
  • 548 ft² Apartment
  • Air Conditioner
  • Parking
  • Pet Friendly

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Property Image From $606
         

New
House
Luxury Beach Home Sauna Cold Plunge E-bikes
  • Sports/Activities
  • Entertainment
  • Child Friendly

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Property Image From $718
         

10.0 (107 Reviews)
House
Serene Escape, Heated Pool, Spa, Outdoor Dining & Putting Green
  • Air Conditioner
  • Parking
  • Pet Friendly

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Property Image From $177
         

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10.0 (7 Reviews)
House
Walk to Beach - Fully Renovated Modern Jax Beach Retreat
  • Air Conditioner
  • Parking
  • View

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Property Image From $432
         

10.0 (4 Reviews)
House
185 m² House ∙ 4 bedrooms ∙ 10 guests
  • 1991 ft² House
  • Air Conditioner
  • Parking
  • Pet Friendly

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Property Image From $199
         

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9.4 (424 Reviews)
Hotel
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
  • Air Conditioner
  • Parking
  • Pool

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Property Image From $676
         

10.0 (105 Reviews)
House
Family-Friendly Luxe Home with Heated Pool & Games
  • Air Conditioner
  • Parking
  • Pet Friendly

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Property Image From $539
         

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New
House
Heated Pool Pet friendly Home
  • Air Conditioner
  • Parking
  • Pet Friendly

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Property Image From $295
         

10.0
House
220 m² House ∙ 3 bedrooms ∙ 10 guests
  • 2369 ft² House
  • Air Conditioner
  • Parking
  • Pet Friendly

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Property Image From $138
         

9.2 (1006 Reviews)
Hotel
Holiday Inn Express Jacksonville Beach by IHG
  • Air Conditioner
  • Parking
  • Pool

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Property Image From $549
         

10.0 (79 Reviews)
House
Coastal Beach Retreat w/Heated Pool, Putting Green
  • Air Conditioner
  • Parking
  • Pet Friendly

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Property Image From $239
         

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10.0 (6 Reviews)
House
{Hidden Gem} Beach Home Blocks from Ocean +6 Bikes
  • Air Conditioner
  • Parking
  • View

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Property Image From $110
         

10.0 (70 Reviews)
Cottage
Private Beachy Guest Cottage!
  • Air Conditioner
  • Parking
  • TV

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Property Image From $334
         

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10.0 (2 Reviews)
House
Coastal Home with Heated Pool Mins to Beach and Mayo!
  • Parking
  • Pet Friendly
  • Pool

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Property Image From $429
         

10.0 (67 Reviews)
House
Stunning Back Patio & Heated Pool
  • Air Conditioner
  • Parking
  • Pet Friendly

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Property Image From $246
         

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10.0 (2 Reviews)
House
Beautiful Beach house with heated pool
  • Air Conditioner
  • Parking
  • Pool

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Property Image From $445
         

10.0 (53 Reviews)
House
Isla's Beach Oasis: Classic Family Beach Oasis with Heated Pool
  • Air Conditioner
  • Parking
  • Pet Friendly

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Property Image From $153
         

10.0 (2 Reviews)
Apartment
Condo near Jax Beach and Mayo Clinic
  • Air Conditioner
  • Parking
  • Pool

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Property Image From $453
         

10.0 (47 Reviews)
House
Family Oasis | Pickleball + Heated Pool & Spa
  • Air Conditioner
  • Parking
  • Pet Friendly

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Property Image From $260
         

10.0 (1 Review)
House
Gem 3
  • Security/Safety
  • Sports/Activities
  • Barbecue/Outdoor Cooking

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Property Image From $499
         

10.0 (43 Reviews)
House
5 BR luxury Beach house 5 min walk to beach
  • Air Conditioner
  • Parking
  • Pet Friendly

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Property Image From $487
         

10.0 (40 Reviews)
House
Spacious Coastal Home with Heated Pool
  • Air Conditioner
  • Parking
  • Pet Friendly

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★ Pro Tip: Floridarentalvacations makes it easy to compare the best listings on Floridarentalvacations homes from online vacation rental OTAs, including Booking.com and more. Use the Advanced Filter feature at the top to easily flip between Floridarentalvacations homes, vacation rentals, bed and breakfasts, private Airbnb-style rentals availability, eco-friendly properties, property type, cancellation policies, prices, and several different options. All these make it easier to find the perfect accommodation for your next vacation in Mayo Clinic Florida.

Weather in Mayo Clinic Florida

View the weather forecast for Mayo Clinic Florida before booking your Mayo Clinic Florida Vacation Rentals to confirm your best time to go.

December - February
High 60°F       Low 26°F
March - May
High 77°F       Low 40°F
June - August
High 91°F       Low 64°F
September - November
High 84°F       Low 38°F

Top Attractions Around Mayo Clinic Florida, FL

Floridarentalvacations offers a large selection of top attractions around Mayo Clinic Florida. Research things to do on your vacation before you visit Mayo Clinic Florida.


St. Johns Town Center TPC Sawgrass Mayport Naval Station University of North Florida Jacksonville University Memorial Hospital Jacksonville Jacksonville Beach Pier Adventure Landing The Avenues Oceanfront Park Kathryn Abbey Hanna Park San Jose Country Club Ponte Vedra Concert Hall Beaches Town Center Kingsley Plantation Saint Vincent's Medical Center Southside Regency Square TPC at Sawgrass Stadium Course Jacksonville Beach Golf Club Morocco Shrine Center